August 2016 News

Scott Hefty (associate professor) is co-Investigator on an NIH Center for Biomedical Research Excellence (COBRE) project that was funded for $11 million.  The grant, entitled “Chemical Biology of Infectious Disease”, is to enable University of Kansas researchers on the Lawrence campus to better contribute to the fight against infectious disease by studying fundamental biology with the use of small molecule chemical probes. Dr. Hefty’s role in the project is to serve as co-investigator for the COBRE and to lead the establishment of an Infectious Disease Assay Development (IDAD) Core to provide expertise, facilities, services, and training in the area of HTS assay design, development, validation, small and large-scale screening for organism (cell) based or biochemical infectious disease targets. Thomas Prisinzano, professor and chair of the Department of Medicinal Chemistry is the Principal Investigator of the grant.

Kristi Neufeld (associate professor) had an article from her laboratory entitled, “Human cancer xenografts in outbred nude mice can be confounded by polymorphisms in a modifier of tumorigenesisrecommended in F1000Prime as being of special significance in its field by F1000 Faculty Member Kent Hunter, Deputy Chief of the Laboratory of Cancer Biology and Genetics at the National Cancer Institute.

 

 

Audrey Lamb (professor) served as co-chair of the Enzymes, Coenzyme and Metabolic Pathways Gordon Research Conference in Waterville Valley, New Hampshire, July 24-29.

 

 

 

Andy Wolfe (graduate student, Neufeld lab) was the recipient of Candlin and MB GSO travel awards to attend the FASEB conference Cell Signaling in Cancer: from Mechanisms to Therapy in Snowmass Village, CO, June 5-10 and present his poster entitled, “Suppression of intestinal tumorigenesis in Apc mutant mice by Musashi-1 deletion”. He also received the E. L. and Mildred Pursell Wolf Scholarship for summer tuition.

 

 

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August 2016 Presentations

Christian Ray (Assistant Professor) gave a talk entitled, “Phenotypic Heterogeneity and Static Protein Distributions in Growth-Arrested Microbes” at the Tenth Annual q-bio Conference at Vanderbilt University in Nashville, TN on July 29.

Matthew Buechner (Associate Professor) gave an invited seminar “Tube Formation in the Model Nematode C. elegans” at the Victor Chang Cardiac Research Institute, Sydney, Australia, on July 21, 2016. 

Mahekta Gujar (graduate student, Lundquist lab) presented a platform talk entitled "UNC-33/CRMP inhibits growth cone protrusion in axon repulsion from UNC-6/netrin” at The Allied Genetics Conference, July 13-17, 2016 in Orlando, FL.

Chad Highfill (Macdonald lab) successfully defended his doctoral dissertation entitled “The complex genetic architecture of lifespan and xenobiotic resistance” on July 5.

Kawaljit Kaur (De Guzman lab) successfully defended her doctoral dissertation entitled “NMR studies of molecular interactions involved in the type III secretion system, sumoylation, and the RNA binding protein HuR” on July 8.

Erin Suderman (Ward lab) successfully defended her masters thesis entitled “Genetic control of tissue specific growth in the Drosophila trachea” on July 7.

Makoto Yoshida (Y. Azuma lab) successfully defended his doctoral dissertation entitled “SUMOylation at the centromere: The role of SUMOylation of the DNA topoisomerase Iiα C-terminal domain in the regulation of mitotic kinases in cell cycle progression” on July 12.

 

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August 2016 Publications

Meneely KM, Sundlov JA, Gulick AM, Moran GR, Lamb AL.  An open and shut case: the role of magnesium in MST enzymes.  J. Am. Chem. Soc.  [Epub ahead of print]

Josephson MP, Miltner AM, Lundquist EA. Non-autonomous Roles of MAB-5/Hox and the Secreted Basement Membrane Molecule SPON-1/F-spondin in Caenorhabditis elegans Neuronal Migration. Genetics. 2016 May 25. pii: genetics.116.188367. [Epub ahead of print]

Reiner DJ, Lundquist EA. Small GTPases. WormBook. 2016 May 24:1-99. doi: 10.1895/wormbook.1.67.2. [Epub ahead of print]

 

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Molecular Biosciences

We are an interdisciplinary group of faculty who perform cutting edge research in a wide range of areas including biochemistry, biophysics, structural biology, bioinformatics, cancer biology, genetics, genomics, immunology, microbiology, virology, neurobiology, molecular, cellular and developmental biology.  We work closely with postdoctoral fellows, graduate students, and undergraduates to investigate fundamental biological problems on all levels from molecules to cells to organisms.  The Department of Molecular Biosciences, located on the Lawrence campus of the University of Kansas system, is an excellent environment for research and education.

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